Diuretiko (Diuretika) ay nagpapataas ng pag-ihi ng katawan, na nagreresulta sa pagbaba ng presyon ng dugo. Simpleng paliwanag: Ang tuloy-tuloy na pag-ihi ng katawan ay nagdudulot ng pagbaba ng dami ng plasma sa dugo at sa gayon ay mas kaunting likido sa mga ugat — bumababa ang presyon sa mga pader ng ugat.
Una sa lahat, ang mga Beta-blocker ay karaniwang ibinibigay sa mga pasyente na may heart failure, aortic aneurysm, pagkatapos ng myocardial infarction, at sa mga kababaihan na nasa edad ng pagbubuntis, lalo na sa mga kababaihang nagpaplano ng pagbubuntis. Madalas matanggap ng katawan ang Beta-blocker, pero maaari rin itong magdulot ng pantal sa balat at bradycardia – sobrang bagal ng tibok ng puso.
Lorista against high blood pressure Minsan, dinadagdagan ng doktor ang base na therapy (mga gamot na kailangang inumin araw-araw) ng mga gamot na iniinom kapag may krisis, kapag ang presyon ay sobrang taas at biglang tumaas. At ang dosis ay pinipili rin nang napaka-indibidwal. Kaya imposible na sabihin kung alin ang pinakamahusay na gamot sa presyon, sa bawat kaso ay magkakaroon ng sariling kombinasyon na bagay sa iyo.
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Diseases of the circulatory System hypertension
Category Cardiovascular Diseases
Medication for dizziness and high blood pressure
Presentation of risk factors for cardiovascular diseases
The main symptoms of diseases of the cardiovascular System
Diabetes mellitus is the cause of cardiovascular diseases
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Lorista as a pharmacological Option for the treatment of high blood pressure Hypertension medical arterial hypertension referred to, constitute a worldwide health problem and is considered to be one of the main risk factors for cardiovascular diseases such as heart attack, stroke, and kidney damage. An effective reduction in blood pressure is, therefore, of crucial importance for the prevention of these life-threatening complications. One of the in the modern therapy of arterial hypertension medicines used Lorista, whose active substance is Losartan. Losartan belongs to the class of Angiotensin‑II‑receptor blocker (in short: ARB or Sartans). Mechanism of action Losartan selectively acts as a competitive Antagonist at the Angiotensin II type‑1 Receptor (AT₁ Receptor). Angiotensin II is a potent vasoconstrictor organic peptides of the Renin‑Angiotensin‑aldosterone‑System (RAAS), which increases blood pressure by: the blood vessels are narrowed (vasoconstriction), the secretion of aldosterone stimulates (which leads to increased sodium and water retention), Sympathetic nervous system activity and promotes. Due to the Blockade of the AT₁ receptors with Losartan prevented the effects of Angiotensin II, Which leads to: a vasodilation (vascular dilation), a decrease in the peripheral vascular resistance, a reduction in aldosterone secretion, and ultimately Reduce the blood pressure. Clinical Efficacy Several randomized controlled trials have demonstrated the efficacy of Losartan in patients with essential hypertension. The gift of Lorista typically leads to a significant drop in both systolic and diastolic blood pressure within 3-6 weeks after initiation of therapy. The effect is dose-dependent, the usual starting dose is 50 mg once daily and 100 mg/day can be increased. Tolerability and side-effects Compared to other blood pressure remedies to inhibitors, in particular, ACE, features Lorista by a better tolerability. A characteristic Problem of ACE‑inhibitors, the persistent dry cough that is caused by the increase of Bradykinin is. Because Losartan does not affect the ACE‑way, this a side-effect, in the case of Lorista much less frequently. Among the possible side effects of Lorista: Dizziness, Headache, Fatigue, Hyperkalemia (increased potassium levels in the blood, especially in patients with renal impairment or concomitant intake of Potassium-sparing diuretics), rare: angioedema. Indications and special patient groups In addition to the treatment of essential hypertension Lorista is also indicated for: Prevention of heart and kidney damage in patients with type 2 Diabetes mellitus and proteinuria, Improve the survival rate after a heart attack, with systolic heart failure (in cases in which ACE inhibitors are not tolerated). Particular caution is advised in patients with bilateral renal artery stenosis, severe liver disease, or during pregnancy, as Sartans, are contraindicated in pregnancy and fetal damage can cause. Conclusion Lorista (Losartan) is a valuable and well-tolerated Option in the pharmacotherapy of arterial hypertension. Its mechanism of action, which is based on the selective Blockade of the Angiotensin II system, provides effective blood pressure control with a favorable side effect profile. The application should always be done under medical supervision and in combination with lifestyle-related measures (such as healthy nutrition, exercise, weight reduction), in order to reduce the overall risk of cardiovascular events in a sustainable way.
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